Oncotarget: A comprehensive analysis of clinical trials in pancreatic cancer

The cover for issue 38 of Oncotarget features Figure 3, «Summary of the time and cost for drug development (modified from DiMasi et al [2016],» by Katayama, et al. which reported that Pancreatic cancer is the most aggressive common cancer and is desperately in need of novel therapies. In this study, the Oncotarget authors perform…

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Study suggests elderly care home outbreaks in England were caused by multiple indepedent infections and also within-home spread

New research presented at this week’s ESCMID Congress on Coronavirus Disease (ECCVID, held online 23-25 September) shows that outbreaks of COVID-19 in elderly care homes were caused by multiple independent infections from outside, plus within care home spread. There is also evidence of transmission between residents and healthcare workers, including paramedics, possibily linking care home…

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Large study confirms men have 62% increased risk of COVID-19 associated death, possibly related to higher degree of inflammation

New research presented at this week’s ESCMID Conference on Coronavirus Disease (ECCVID, online 23-25 September) confirms that men with COVID-19 have worse outcomes than women, possibly related to them experiencing higher levels of inflammation. The study is by Dr Frank Hanses, University Hospital Regensburg, Germany, and colleagues, and shows that men have a 62% increased…

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Your neighborhood may raise your risk of chronic kidney disease

A neighborhood’s overall socioeconomic status, including income and education level, may influence its residents’ risk of chronic kidney disease, according to a study recently published in SSM Population Health by researchers from Drexel University’s Dornsife School of Public Health. Although previous studies have shown an association between individual socioeconomic status and chronic kidney disease, less…

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UofA lab uncovers new mechanism of action against SARS-CoV-2 by antiviral drug remdesivir

Researchers at the University of Alberta have discovered a novel, second mechanism of action by the antiviral drug remdesivir against SARS-CoV-2, according to findings published today in the Journal of Biological Chemistry. The research team previously demonstrated how remdesivir inhibits the COVID-19 virus’s polymerase or replication machinery in a test tube.  Matthias Götte, chair of…

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Over 200,000 People Have Died in the US: Live Covid-19 Updates

Here’s what you need to know: ImageVanessa Acosta gives a lecture using an online platform from her empty classroom in Miami Lakes, Fla., on Aug. 31.Credit…Cristobal Herrera-Ulashkevich/EPA, via Shutterstock Miami-Dade County, Fla., one of the largest school districts in the U.S., will reopen classrooms to students next month. Students in Miami-Dade County, the fourth-largest district…

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