Imaging probe to visualize Alzheimer’s disease-related gamma-secretase in the brain

BOSTON — Scientists at the Massachusetts General Hospital (MGH) have developed a molecular imaging probe to reveal Alzheimer’s disease (AD)-related γ-secretase in rodents and macaques with translational potentials in humans. γ-Secretase is a key player in the etiology of AD and a prime drug target for AD, whose brain regional expression and distribution have yet…

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Snapshots of an Extraordinary Moment in Time

At 3 a.m. from my bathroom window the call of an owl breaking the night’s silence. —Leota Fulkerson, 65, South Thomaston, Maine Last week, I suggested keeping a log book, a low-key journal where you note the mundane things that happen in a day, to keep a record of moments you’re likely to forget. I…

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Maya Moore of W.N.B.A. Weds Jonathan Irons, Inmate She Helped Free

A journey for justice turned into a love story when Maya Moore, one of the W.N.B.A.’s brightest stars, married the man she helped free from prison. The man, Jonathan Irons, walked out of a Missouri prison on July 1 — more than 20 years after he was convicted on charges of burglary and assault. Mr.…

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Diversity: A Movement, Not a Moment

Slow and steady in its progress, the scrappy indie incubator known as NYMD (for New York Men’s Day) finally managed to slip into the big top this week with a full morning of digital shows run under the banner of the Council of Fashion Designers of America. Although in its early days NYMD got little…

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The Vikings Were More Complicated Than You Might Think

Public fascination with the Vikings runs high these days, with several current television series available for bloody binge-watching. But the Vikings have never really gone out of fashion, whether as pure entertainment or because of their real historical importance. Periodically, scholars remind the public that the people we call Vikings did not think of themselves…

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Harlem’s Fashion Row Designers Created the Coolest Kids Collection

Janie and Jack rolls out very cute wares for the small set seasonally. But its most recent collection has a more high fashion bent— a collaboration on a children’s collection with Harlem’s Fashion Row, founded in 2007 by Brandice Daniel as a platform for multi-cultural designers. And BAZAAR has a sneak peek at three of…

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The Hosts of ‘Back Issue’ Want to Throw It Back

Remember when watching the sitcoms “Martin” and “Living Single” or the variety show “In Living Color” meant that it was the end of the day and it was time to have a laugh? Or when Tyra Banks gave her now iconic “We were rooting for you!” rant on “America’s Next Top Model?” On “Back Issue,”…

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Oculus Quest 2 Review: Solid V.R. Headset, but Few Games

A group of five boxers and I recently threw punches to upbeat music while an instructor egged us on. By the end of the 20-minute workout, I’d broken a sweat and my smartwatch showed my heart rate thumping at 140 beats a minute. Normally, this would be the result of a workout at my local…

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Covid-19 Vaccines Will Be Free for Americans, Warp Speed Officials Say

Federal officials outlined details Wednesday of their preparations to administer a future coronavirus vaccine to Americans, saying they would begin distribution within 24 hours of any approval or emergency authorization, and that their goal was that no American “has to pay a single dime” out of their own pocket. The officials, who are part of…

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