Popular painkiller ibuprofen affects liver enzymes in mice

The popular painkiller ibuprofen may have more significant effects on the liver than previously thought, according to new research from the University of California, Davis. The study in laboratory mice also shows marked differences between males and females. The work is published Feb. 25 in Scientific Reports. Ibuprofen belongs to a group of drugs called…

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BIN1 deficit impairs brain cell communication, memory consolidation

TAMPA, Fla (March 11, 2020) — Bridging integrator 1, known as BIN1, is the second most common risk factor for late-onset Alzheimer’s disease, according to genome-wide studies of genetic variants. Yet, scientists know little about what this protein does in the brain. Now a new preclinical study has discovered that a lack of BIN1 leads…

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Like patching a flat tire: New fix heals herniated discs

ITHACA, N.Y. — A new two-step technique to repair herniated discs uses hyaluronic acid gel to re-inflate the disc and collagen gel to seal the hole, essentially repairing ruptured discs like you’d repair a flat tire. After a rupture, a jelly-like material leaks out of a herniated disc, causing inflammation and pain. The injury is…

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Probing the genes that organize early brain development

When brains begin developing, there are a lot of moving parts — and when mutations happen in early neurodevelopment, it can lead to disorders like macrocephaly and autism. But scientists don’t know much about the ways that development goes askew, particularly in humans. That’s why Wei Zhang, a postdoctoral scholar and research associate at USC’s…

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People want more compensation, security for their genomic data

ITHACA, N.Y. — Genomic data donated by the public is valuable for the companies that collect it. But a recent survey finds that once people are aware of issues surrounding the use and security of genetic information, people are more concerned about how it might be used and expect to be better compensated for providing…

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Sensing infection, suppressing regeneration

In a new peer-reviewed publication, University of Illinois at Chicago researchers describe how the body’s response to inflammation, which helps to fight many kinds of infections, also can counterproductively suppress much-needed cell repair and regeneration in blood vessels. In the study, which is published in Immunity, the researchers describe an enzyme that blocks the ability…

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First Coronavirus Death in New Jersey: Yonkers Raceway Worker

A New Jersey man who worked at a racetrack just north of New York City died on Tuesday after contracting the coronavirus — the first known fatality in the Northeast linked to the virus. Yonkers Raceway, the popular harness-racing track, shut down Tuesday afternoon and has asked employees who spent time near the horse paddock…

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Coachella, Influential Music Festival, Is Postponed Amid Virus Fears

Coachella is postponed. Organizers of the Coachella Valley Music and Arts Festival, the giant pop festival in the picturesque desert of Southern California, have delayed next month’s event to October over concerns about the coronavirus, the festival announced on Tuesday after days of speculation. The festival, which had been planned in two weekend installments, April…

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