2017 pneumonic plague outbreak in Madagascar characterized by scientists

Plague is an endemic disease in Madagascar. Each year there is a seasonal upsurge between September and April, especially in the Central Highlands, which stand at an elevation of more than 800m. In 2017, an unprecedented pneumonic plague outbreak hit the main island, primarily affecting the capital Antananarivo and the main port city of Toamasina.…

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New role for innate immune sensor: Suppressing liver cancer

IMAGE: Drs. Hasan Zaki (left) and SM Nashir Udden. view more  Credit: UTSW DALLAS — April 15, 2019 — UT Southwestern researchers have found that a protein in the body’s innate immune system that responds to gut microbes can suppress the most common type of liver cancer. The study, published today in the journal eLife, determined…

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Probing the mystery of drug resistance: New hope for leukemia’s toughest cases

IMAGE: This is Alejandro Gutierrez, MD. view more  Credit: MICHAEL GODERRE / BOSTON CHILDREN’S HOSPITAL Three children Alejandro Gutierrez, MD, treated for leukemia during his fellowship at Boston Children’s Hospital still haunt him more than a decade later. One 15-year-old boy died from the toxicity of the drugs he was given; the other two patients went…

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The pressure to prescribe: Antibiotic stewardship in the outpatient setting

Arlington, Va., April 16, 2019 — Outpatient healthcare providers inappropriately prescribed antibiotics to 40 percent of patients in a major Veterans Affairs healthcare system, a higher figure than in previous studies examining outpatient antibiotic use, according to a new study appearing in the American Journal of Infection Control (AJIC), the journal of the Association for…

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AI performs as well as experienced radiologists in detecting prostate cancer

FINDINGS UCLA researchers have developed a new artificial intelligence system to help radiologists improve their ability to diagnose prostate cancer. The system, called FocalNet, helps identify and predict the aggressiveness of the disease evaluating magnetic resonance imaging, or MRI, scans, and it does so with nearly the same level of accuracy as experienced radiologists. In…

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The fluid that feeds tumor cells

IMAGE: Pancreatic cancer cells (nuclei in blue) growing as a sphere encased in membranes (red). By growing cancer cells in the lab, researchers can study factors that promote and prevent the… view more  Credit: Min Yu (Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC) CAMBRIDGE, MA — Before being tested…

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FIU scientists discover new arsenic-based broad-spectrum antibiotic

IMAGE: FIU researchers Adriana Emilce Galvan, Masafumi Yoshinaga, Kunie Sakurai, Venkadesh Sarkarai Nadar, Jian Chen, Barry Rosen. Photographed in Rosen’s lab at Herbert Wertheim College of Medicine. view more  Credit: Doug Garland, FIU Antibiotic resistance has been called one of the biggest public health threats of our time. There is a pressing need for new and…

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