Prescription drug costs steadily soar, yet price transparency is lacking

LA JOLLA, CA – After reviewing tens of millions of insurance claims for the country’s 49 most popular brand-name prescription drugs, a team from Scripps Research Translational Institute found that net prices rose by a median of 76 percent from January 2012 through December 2017—with most products going up once or twice per year. The…

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ASCO: Finally, a tool to predict response to chemotherapy before bladder cancer surgery

IMAGE: Thomas Flaig, MD, and colleagues show that COXEN may predict which patients will respond to chemotherapy before bladder cancer surgery view more  Credit: University of Colorado Cancer Center University of Colorado Cancer Center led clinical trial data show that a predictive tool called COXEN may show which bladder cancer patients will respond to pre-surgical chemotherapy,…

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Astrocytes protect neurons from toxic buildup

Astrocytes are overtaxed neurons’ pit crew. The brain cells collect damaged lipids secreted by hyperactive neurons, then recycle those toxic molecules into energy, researchers at the Howard Hughes Medical Institute’s Janelia Research Campus report May 23, 2019, in the journal Cell. It’s a mechanism to protect neurons from the damaging side effects of overactivity. And…

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A small electrical zap to the brain could help you retrieve a forgotten memory

IMAGE: This is Jesse Rissman in his UCLA office. view more  Credit: Stuart Wolpert/UCLA A study by UCLA psychologists provides strong evidence that a certain region of the brain plays a critical role in memory recall. The research, published in the Journal of Cognitive Neuroscience, also shows for the first time that using an electrical current…

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Can cannabinoids help treat obsessive-compulsive disorder?

IMAGE: Cannabis and Cannabinoid Research is the premier journal dedicated to the scientific, medical, and psychosocial exploration of clinical cannabis, cannabinoids, and the biochemical mechanisms of endocannabinoids. For more information, visit… view more  Credit: ©2012, Mary Ann Liebert, Inc., publishers New Rochelle, NY, May 30, 2019—The body’s endocannabinoid system, due to the critical role it plays…

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36 Hours in Bend, Ore. (and Environs)

Residents of Bend unite around the core conviction that they live in a beautiful place. But great beauty also inspires an undercurrent of concern that this mountain town’s natural splendor will be imperiled if too many people show up and spoil the place. A popular local bumper sticker reads, “Bend Sucks, Don’t Move Here,” and…

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Stress Early in Pregnancy Tied to Lower Sperm Counts in Adult Sons

Stress early in pregnancy is associated with reduced sperm counts and lower testosterone levels in adult sons, a new study has found. The study, in Human Reproduction, included 643 men, 407 of whose mothers had been exposed to a stressful event within the first 18 weeks of pregnancy: death of a relative or friend, job…

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Fighting the Gender Stereotypes That Warp Biomedical Research

Say you are prescribed medication for depression, anxiety or even just to sleep. Would you want to take it if you knew that the drug had only been tested on men and male animals? Rebecca Shansky, a neuroscientist at Northeastern University in Boston, thinks you might not. When she tells nonscientific audiences that researchers “for…

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