Platinum-based chemo may improve survival for some metastatic pancreatic cancer patients

Bottom Line: Patients with metastatic pancreatic cancer who had germline or somatic mutations in DNA repair genes had better clinical outcomes after platinum-based chemotherapy, as compared with patients without these mutations. Journal in Which the Study was Published: Clinical Cancer Research, a journal of the American Association for Cancer Research Authors: The senior author was…

Details

$1.2 Billion From U.S. to Drugmaker to Pursue Coronavirus Vaccine

The deal with AstraZeneca is the fourth and by far the largest vaccine research agreement that the department has disclosed. The money will pay for a Phase 3 clinical trial of a potential vaccine in the United States this summer with about 30,000 volunteers. The H.H.S. statement said the agency and AstraZeneca “are collaborating to…

Details

Prominent Scientists Denounce End to Coronavirus Grant

A group of 77 Nobel laureates has asked for an investigation into the cancellation of a federal grant to EcoHealth Alliance, a group that researches bat coronaviruses in China. The pre-eminent scientists characterized the explanation for the decision by the National Institutes of Health as “preposterous.” The agency said the investigation into the sources of…

Details

Tech Is a Citadel. Del Seymour Built a Drawbridge.

SAN FRANCISCO — On his walking tours of the Tenderloin, a historically seamy neighborhood named for a cut of beef, Del Seymour passes Boeddeker Park, now a verdant jewel of urbanity. Eleven years ago, it was a notorious hellhole where Mr. Seymour, then a crack addict, dealer and pimp, shooed away do-gooders from the local…

Details

A New Site to Help Rescue New York Restaurants

An initiative called SaveTheEats is working to consolidate support for many restaurants that have closed or are struggling to remain open during the coronavirus pandemic. On Tuesday, New York City joined the growing list of participating cities on its website, including Philadelphia (where #SavePHILLYEats started on March 31), Washington, Minneapolis-St. Paul, Baltimore, Los Angeles and…

Details

What Comes After a 2-Month Quarantine Date?

My guy and I have been seeing each other since August, and our relationship is going great. For the past two months, we’ve been sheltering in place together at his home (which is 90 minutes away from mine). We’ve been having lots of fun: great conversations, making art, listening to music and still getting our…

Details

Awesome Home Storage Ideas

Nowadays free home space is becoming a luxury, especially if you live in a city. Because when you live in a metropolis, you normally live in an apartment. And a square meter of it costs so much you can’t afford to have a large one. If you’re a few people you have things you need…

Details

Our Best Memorial Day Recipes

Summer may officially begin on the solstice, the longest day of the year, but the unofficial start to the season is the long Memorial Day weekend, when many home cooks dust off their grills and declare that cookout season begun. This year might look a little different — maybe you’re cooking for your “quaranteam” or…

Details

10 Great Bottles of Italian White Wine Under $25

Regardless of the ubiquity of pinot grigio and Prosecco, the antiquated notion of Italy as solely a red wine culture retains its tenacious grip on the imagination. It was not true 20 years ago, and it’s not true today. Italy makes more wine than any other country on earth, and it might surprise you, as…

Details

What Is New York Without New York Bars?

I miss bars. I miss the noise, the jostling shoulders and the promise the night offers. I miss a long, dark pour of Guinness and the gleaming liquor bottles standing sentry behind the bartender. I miss the crush for the ladies’ room, graffiti decades thick. I miss the endless possibility in conversations overheard, lives intersecting.…

Details