Sickle-Cell Treatment Created With Gene Editing Wins U.K. Approval

Regulators in Britain on Thursday approved the first treatment derived from CRISPR, the revolutionary gene-editing method. Called Casgevy, the treatment is intended to cure sickle-cell disease and a related condition, beta thalassemia. The manufacturers, Vertex Pharmaceuticals, based in Boston, and CRISPR Therapeutics, based in Switzerland, say about 2,000 patients in Britain with sickle-cell disease or…

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How to Skip the Turkey

We’re one week out from Thanksgiving, and you need showstopping sides (read to the very end for rapid-fire recipes) and meatless mains and dairy-free desserts, and you need them stat. So let’s not waste a moment of time. This … is Recipe Matchmaker. Replacing the Turkey “I am looking for a stand-in main dish to…

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Thanksgiving Wines Under $20

By now, your Thanksgiving preparations may nearly be set. You are on top of the menu, who’s cooking what, seating, tasks for the children. But what about the wine? This is the easy part of holiday planning, with just a few guiding principles to keep in mind. If you’re having a big party, don’t worry…

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