Partners in Business, Parenthood and Marriage (in Any Order)

Almost nothing about Kayla Picciuto and Andrew Elia’s relationship has been traditional or expected. The two spent more time casually peering at each other at a local coffee shop than they did actually dating, and they started an event entertainment business, Party Proper Productions, together at the same time they became girlfriend and boyfriend. Then…

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This Zucchini Tian Is Nonna-Inspired Cooking at Restaurant Speed

There was always a little static while trying to bring my lo-fi home cooking into a restaurant setting, producing it at restaurant speed and volume, pace and temperature, and getting it back on the plate in such a way that would still remind you of good home cooking. In spite of its stainless-steel countertops and…

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New insights into mechanism of therapy to reduce liver fat and prevent fibrosis

BOSTON — A team led by researchers at Massachusetts General Hospital (MGH) has taken an important step forward in the goal of developing a potential treatment for non-alcoholic fatty liver disease (NAFLD), the most common form of chronic liver disease. There are currently no approved medications for NAFLD, but in a study published in the…

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Overlooked ‘housekeeping’ gene plays unexpected role in seizures

Within cells, molecules known as transfer RNAs, or «tRNAs,» play an important but unglamorous workhorse role in keeping the genetic translation process moving along from codes of DNA to functional proteins. Because they play such a vital role in this translational «housekeeping,» tRNAs are plentiful. There are hundreds of tRNA genes in mammalian cells and…

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Learning how one element—zinc—helps millions of nerve cells communicate

Zinc isn’t just an ingredient in the lozenges you might take when you feel a cold coming on. It’s also crucial to communication among the neurons—or nerve cells—in your brain, whether those neurons are helping you remember what lozenges to buy or eavesdrop on a conversation in the next pharmacy aisle. According to Charles Anderson—a…

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Tethering together type 2 diabetes drugs increases efficacy of combination therapy

DURHAM, N.C. — Biomedical engineers at Duke University have shown that the efficacy of a two-pronged type 2 diabetes treatment increases when the drugs are linked by a heat-sensitive tether rather than simply concurrently administered. The combination molecule is formed by an elastin-like polypeptide (ELP) linker that forms a gel-like depot when injected under the…

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New study explores symptomatology, quality of life before and after labiaplasty

August 26, 2020 — For patients with elongated labia, vague terms like «vaginal rejuvenation» and «designer vagina» can undermine the seriousness of the condition, which includes a variety of functional concerns. Often attributed to congenital causes, exogenous hormones, chronic irritation, childbirth, aging and external physical causes, women at nearly every age, from birth to later…

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Researchers unravel two mysteries of COVID-19

LONDON, ONTARIO — A team from Lawson Health Research Institute and Western University has made significant steps forward in understanding COVID-19 through two back-to-back studies published this week in Critical Care Explorations. In one study, the team has identified six molecules that can be used as biomarkers to predict how severely ill a patient will…

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New Mass. poll: Markey up 12 points in US Senate primary

LOWELL, Mass. — Incumbent Edward Markey has opened up a double-digit lead over challenger U.S. Rep. Joseph Kennedy III one week before the Democratic primary in the race for U.S. Senate, according to a new poll of Massachusetts voters released today. Conducted by the UMass Lowell Center for Public Opinion, the poll of 800 likely…

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