Yale scientists propose explanation for baffling form of childhood OCD

Yale scientists may have found a cause for the sudden onset of obsessive-compulsive disorder (OCD) in some children, they report. Pediatric autoimmune neuropsychiatric disorders, or PANDAS, were first proposed in the 1990s. Thought to be triggered by streptococcal infections, they account for an unknown portion of youth OCD cases. But the biology underpinning this disorder…

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How does our brain trigger different sighs? New findings could provide answers

One group of neurons controls various types of sighing, but they receive their instructions from different areas of the brain depending on the reason for the sigh, according to a study scheduled to publish June 16 in the journal Cell Reports. Humans and other mammals sigh automatically once every few moments­ to maintain proper lung…

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Children with developmental disabilities more likely to develop asthma

Children with developmental disabilities or delay are more at risk of developing asthma, according to a new study published in JAMA Network Open led by public health researchers at The University of Texas Health Science Center at Houston (UTHealth) as part of the Center for Pediatric Population Health. Using data from the 2016-2017 National Survey…

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Exercise offers ‘profound’ benefits for Friedreich’s ataxia, research suggests

A top exercise researcher at the University of Virginia School of Medicine is urging clinical trials of exercise in patients with Friedreich’s ataxia after finding that physical activity has a «profound» protective effect in mouse models of the debilitating genetic disease. Friedreich’s ataxia typically limits patients’ ability to exercise. But the new findings from UVA’s…

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New mechanism underlying colorectal cancer reveals a crucial role for intestinal microbes

A collaborative study by research groups from the VIB-UGent Center for Inflammation Research and Ghent University uncovered a new mechanism causing colorectal cancer. The researchers found that abnormal expression of the protein Zeb2 affects the integrity of the intestinal wall or ‘epithelium’. This epithelium normally functions as a barrier to prevent infiltration by intestinal microbes.…

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Including patients in hospital discharge communication would improve outcomes of care

Study by University of Warwick researchers shows UK patients are keen to receive discharge letters when they leave hospital UK hospitals send discharge letters to GPs as part of care handover, but practice of copying in patients is inconsistent Better information for patients following discharge from hospital could improve the outcomes of care, including avoiding…

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NCRI Virtual: In conversation with…Vinay Prasad

Join Dr Vinay Prasad, a Haematologist-Oncologist and Associate Professor of Medicine at University of California San Francisco. Vinay studies cancer drugs, health policy and evidence-based medicine and, in conversation with Dr Richard Simcock from Brighton and Sussex University Hospitals NHS Trust, will discuss ‘the good, the bad and the ugly’ in clinical research; what we can…

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Coronavirus Study: 1 in 5 People Worldwide at Risk

In just six months, nearly 8 million people worldwide have been stricken with confirmed cases of Covid-19, and at least 434,000 have died. But those deaths have not been distributed evenly; among the most vulnerable are people with underlying health conditions, such as diabetes and diseases that affect the heart and lungs. According to a…

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