Gathering big data to accelerate the COVID-19 fight

A nationwide collaboration of clinicians, informaticians and other biomedical researchers aims to turn data from hundreds of thousands of medical records from coronavirus patients into effective treatments and predictive analytical tools that could help lessen or end the global pandemic. Through the National COVID Cohort Collaborative, about 60 clinical institutions affiliated with the National Institutes…

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Extraction of skin interstitial fluid using microneedle patches

(LOS ANGELES) — The interstitial fluid is a major component of the liquid environment in the body and fills the spaces between the body’s cells. In contrast, blood circulates only within the circulatory vessels of the body and is composed of blood cells and the liquid part of the blood, plasma. Both fluids contain special…

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Strong convictions can blind us to information that challenges them

When people are highly confident in a decision, they take in information that confirms their decision, but fail to process information which contradicts it, finds a UCL brain imaging study. The study, published in Nature Communications, helps to explain the neural processes that contribute to the confirmation bias entrenched in most people’s thought processes. Lead…

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Ivy Brain Tumor Center launches new clinical trial for recurrent glioblastoma

The Ivy Brain Tumor Center at Barrow Neurological Institute announced that patient recruitment has opened for a new Phase 0 clinical trial to evaluate two targeted therapy drugs, abemaciclib and LY3214996. The study will evaluate central nervous system (CNS) penetration in patients with recurrent glioblastoma scheduled for resection. This is the first time a combination…

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A versatile antiviral emerges to fight COVID-19

Scientists everywhere are working overtime to develop treatments for COVID-19, the disease caused by the novel coronavirus SARS-CoV-2. Many existing drugs and new candidates are being tested, with the hope of easing the global pandemic ahead of a vaccine. An article in Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society, reports…

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Bullying is common factor in LGBTQ youth suicides, YSPH study finds

Researchers at the Yale School of Public Health have found that death records of LGBTQ youth who died by suicide were substantially more likely to mention bullying as a factor than their non-LGBTQ peers. The researchers reviewed nearly 10,000 death records of youth ages 10 to 19 who died by suicide in the United States…

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The evolutionary puzzle of the mammalian ear

The vertebrate ear is a remarkable structure. Tightly encapsulated within the densest bone of the skeleton, it comprises the smallest elements of the vertebrate skeleton (auditory ossicles) and gives rise to several different senses: balance, posture control, gaze stabilization, and hearing. Nowhere else in the vertebrate skeleton are different functional units packed so close together…

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New cancer immunotherapy targeting myeloid cells slows tumor growth

PHILADELPHIA — Checkpoint inhibitors, a type of immunotherapy, that target myeloid immune cells and slow tumor growth were discovered by a team from the Perelman School of Medicine at the University of Pennsylvania and other institutions. Reporting in Nature Cancer, the researchers showed for the first time in human cells and a mouse model that…

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In Quarantine, Restaurant Recipes Are Postcards From Another Time

Gourmet used to run a recipe-request column called You Asked For It. It was everybody’s favorite part of the magazine. Everybody, that is, except Gourmet’s test-kitchen cooks, who drove themselves crazy getting the recipes into a form that people at home could follow. In Gourmet’s early years, the 1940s and ’50s, what readers asked for…

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