Konstanz biologists honored for promoting animal welfare

Marcel Leist, Professor of In-Vitro Toxicology and Biomedicine at the University of Konstanz, and Thomas Hartung, Professor of Environmental Health Sciences at the University of Konstanz and Doerenkamp-Zbinden Chair of Evidence-Based Toxicology at Johns Hopkins Bloomberg School of Public Health in Baltimore, have been awarded the Ursula M. Händel Animal Welfare Prize 2020 of the…

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Minimally invasive percutaneous treatment for osteoid osteoma of the spine

This research defines the new mini-invasive technique for the treatment of osteoid osteomas, which are benign but painful bone-forming tumors that usually involve long bones, with 10-20% of the cases having localization at the spine. The most common symptom in osteoid osteomas is back pain which is generally responding to nonsteroidal anti-inflammatory drugs, but in…

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Youth more likely to stick with CGM if they are part of decision to start

Philadelphia, July 31, 2020—Continuous glucose monitoring (CGM) tracks glucose levels of people with type I or type II diabetes through a device that monitors levels throughout the day. These devices improve control of blood sugar levels by alerting patients when their levels go too high or low, but patients need to use the technology consistently…

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Insight on novel genetic approaches to metabolic liver diseases

DETROIT — Diabetes, obesity and nonalcoholic fatty liver disease (NAFLD) are all common diseases that can lead to serious health implications. NAFLD affects over 30% of Americans, and is characterized as a fatty liver, which can progress to an inflammatory and fibrotic liver, called nonalcoholic steatohepatitis (NASH), as well as liver cirrhosis. The molecular causes…

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Damon Runyon Cancer Research Foundation awards fellowships to 15 young scientists

Grants totaling nearly $3.5 million give early career investigators independence to pursue brave and bold cancer research. Fifteen scientists from across the country were named Damon Runyon Fellows. The recipients of this prestigious, four-year award are outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators. The Fellowship encourages…

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Epilepsy: International researchers propose better seizure classification

Epilepsy is a wide-spread neurological disorder that affects around 50 million people worldwide. It is characterized by recurrent epileptic seizures, which are sudden bursts of electrical activity in the brain. There are many different types of seizures, and a person with epilepsy can experience more than one type. Clinicians today use EEG measurements, with electrodes…

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‘Little brain’ or cerebellum not so little after all

When we say someone has a quick mind, it may be in part thanks to our expanded cerebellum that distinguishes human brains from those of macaque monkeys, for example. Sometimes referred to by its Latin translation as the ‘»little brain»‘, the cerebellum is located close to the brainstem and sits under the cortex in the…

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A simple screening process may enhance monoclonal antibody-based drug development

By screening potential monoclonal antibody (mAb)-based drugs solely based on a measure of their colloidal stability, scientists may be able to weed out mAbs that do not respond efficiently in solution early in the drug discovery process, according to a new study. This finding could enable researchers to overcome a major hurdle to drug development…

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