Designed antiviral proteins inhibit SARS-CoV-2 in the lab

Computer-designed small proteins have now been shown to protect lab-grown human cells from SARS-CoV-2, the coronavirus that causes COVID-19. The findings are reported today, Sept. 9, in Science In the experiments, the lead antiviral candidate, named LCB1, rivaled the best-known SARS-CoV-2 neutralizing antibodies in its protective actions. LCB1 is currently being evaluated in rodents. Coronaviruses…

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Small proteins against SARS-CoV-2 neutralize infection in cell culture

Using innovative computer-based approaches, researchers have developed protein inhibitors that block the interaction between the SARS-CoV-2 virus and human cell receptor ACE2. In cell culture, the most potent of these inhibitors could neutralize virus infection, paving the way for their use in therapies that could be delivered more easily than antibodies. SARS-CoV-2 infection generally begins…

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Special journal issue features Nemours heart specialists’ best practices for children

JACKSONVILLE, Fla. (September 9, 2020) — The September issue of Progress in Pediatric Cardiology will exclusively feature articles by pediatric cardiologists at Nemours Children’s Health System on echocardiography and other cardiac imaging techniques used in the care of children with cardiovascular disease. The 15 original papers and four case studies highlight best practices for imaging…

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ENT physicians and researchers showcase studies at Otolaryngology’s Virtual Annual Meeting

ALEXANDRIA, VA— During the AAO-HNSF 2020 Virtual Annual Meeting & OTO Experience, which runs from September 13 through October 25, the most current research in otolaryngology-head and neck surgery will be introduced during the Scientific Oral Presentations. Scientific Oral Presentations are a series of three- to six-minute presentations focusing on current evidence-based research, surgical procedures,…

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New vaccine design reduces inflammation, enhances protection

Adjuvants are a key ingredient of many modern vaccines, working to unleash an immune response that helps protect the body from disease. Many scientists believe that adjuvants are they key to developing new kinds of vaccines for hard-to-vaccinate viruses, like HIV. But adjuvants can cause inflammation at the injection site, as well as side effects…

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Vaccine proponents and opponents are vectors of misinformation online

In a new paper published in the Harvard Kennedy School Misinformation Review, researchers from the George Washington University, University of Maryland and Johns Hopkins University assessed content from the most active vaccine-related accounts on Twitter and found that even accounts with pro-vaccination views and higher public health credibility can be vectors of misinformation in the…

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RIT/NTID researchers study how deaf and hearing people watch sign language

A recent study has shown that readers’ eye gaze behaviors are strong indicators of words that are unexpected, new, or difficult to understand. The study by Rain Bosworth, an assistant professor and researcher in the Center for Sensory, Perceptual, and Cognitive Ecology (SPaCE Center) at Rochester Institute of Technology’s National Technical Institute for the Deaf,…

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AstraZeneca Pauses Vaccine Trial for Safety Review

The pharmaceutical company AstraZeneca halted large, late-stage global trials of its coronavirus vaccine on Tuesday because of a serious suspected adverse reaction in a participant, the company said. It is not yet known whether the reaction was directly caused by the company’s vaccine or was coincidental. The pause, which was first reported by STAT, will…

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