Group A strep genome research expedites vaccine development efforts

The global search for a group A streptococcal (Strep A) vaccine has narrowed after researchers identified a common gene signature in almost all global Strep A strains by sequencing thousands of genomes in a project spanning 10 years and more than 20 countries. Strep A, is a bacterial pathogen that in some regions of the…

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Global Strep A vaccine one step closer

The search for a global Strep A vaccine has narrowed after researchers sequenced the DNA of more than 2000 Group A Streptococcus samples from around the world. Researchers from the Wellcome Sanger Institute, the University of Cambridge, the Peter Doherty Institute for Infection and Immunity (Doherty Institute) in Australia, and the University of Queensland, Australia,…

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Coat of proteins makes viruses more infectious and links them to Alzheimer’s disease

IMAGE: Proteins in the fluid surrounding the target cell bind to a virus and can make it more infectious. The virus can also accelerate the formation of threadlike amyloid fibrils that… view more  Credit: E. Wikander/Azote/Stockholm University New research from Stockholm University and Karolinska Institutet shows that viruses interact with proteins in the biological fluids of…

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Artificial intelligence detects a new class of mutations behind autism

IMAGE: Ogla Troyanskaya is a professor of computer science and the Lewis-Sigler Institute for Integrative Genomics at Princeton University. view more  Many mutations in DNA that contribute to disease are not in actual genes but instead lie in the 99% of the genome once considered «junk.» Even though scientists have recently come to understand that these…

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Brain stimulation enhances visual learning speed and efficiency

Practice results in better learning. Consider learning a musical instrument, for example: the more one practices, the better one will be able to learn to play. The same holds true for cognition and visual perception: with practice, a person can learn to see better—and this is the case for both healthy adults and patients who…

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NMR structure of a key anticoagulant protein may help prevent thrombosis

IMAGE: 1) NMR data was used to the structure determination and 2) interaction site mapping and 3) all data was used to construct a model of the complex. view more  Credit: Ana Paula Valente A collaboration between researchers from Brazil and the United States may open new avenues for the treatment of thrombosis, the leading cause…

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New causes of autism found in ‘junk’ DNA

Leveraging artificial intelligence techniques, researchers have demonstrated that mutations in so-called ‘junk’ DNA can cause autism. The study, published May 27 in Nature Genetics, is the first to functionally link such mutations to the neurodevelopmental condition. The research was led by Olga Troyanskaya in collaboration with Robert Darnell. Troyanskaya is deputy director for genomics at…

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Colliding lasers double the energy of proton beams

IMAGE: A standard laser generated proton beam is created through firing a laser pulse at a thin metallic foil. The new method involves instead first splitting the laser into two less… view more  Researchers from Sweden’s Chalmers University of Technology and the University of Gothenburg present a new method which can double the energy of a…

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