New immunotherapeutic approach takes aim at cancer’s enzyme shield

Immunotherapies have transformed the landscape of cancer treatment by allowing physicians to alter or augment patients’ immune response to better attack malignant tumors. But some tumors — known as «cold tumors» — fly under the immune system’s radar. Checkpoint inhibitors, which are the basis of many immunotherapies, don’t work well against them. A team of…

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COVID-19 may deepen depression, anxiety, and PTSD among pregnant and postpartum women

Boston — Though childbirth is often anticipated with optimism and enthusiasm, approximately 10 to 20 percent of pregnant individuals also experience mental health challenges during the weeks immediately before and after birth. Depression, anxiety and trauma-related disorders can all be exacerbated by increased stress related to pregnancy and postpartum experiences. But it’s unknown how the…

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OHDSI awarded $10 MM FDA contract to monitor safety/effectiveness of vaccines, biologics

NEW YORK, NY (Dec. 1, 2020)—Researchers within the Observational Health Data Services and Informatics (OHDSI) community were recently awarded a $10 million contract from the U.S. Food and Drug Administration (FDA) to provide support to the Biologics Effectiveness and Safety (BEST) program, which was launched by the FDA Center for Biologics Evaluation and Research (CBER)…

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Vitamin D regulates calcium in intestine differently than previously thought

A Rutgers study has discovered that vitamin D regulates calcium in a section of the intestine that previously was thought not to have played a key role. The findings have important implications on how bowel disease, including ulcerative colitis and Crohn’s disease, may disrupt calcium regulation. In a healthy person, the body absorbs calcium to…

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New device offers faster way to detect antibiotic-resistant bacteria

BINGHAMTON, NY — Bacterial infections have become one of the biggest health problems worldwide, and a recent study shows that COVID-19 patients have a much greater chance of acquiring secondary bacterial infections, which significantly increases the mortality rate. Combatting the infections is no easy task, though. When antibiotics are carelessly and excessively prescribed, that leads…

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Football-loving states slow to enact youth concussion laws

PULLMAN, Wash. — States with college teams in strong conferences, in particular the Southeastern Conference (SEC), were among the last to take up regulations on youth concussions, according to a recent study. The study, which investigated the association between youth sport participation and passage of concussion legislation, uncovered the importance of SEC affiliation, and found…

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Vaccines Are Coming, but Pandemic Experts Expect a ‘Horrible’ Winter

Each week, good news about vaccines or antibody treatments surfaces, offering hope that an end to the pandemic is at hand. And yet this holiday season presents a grim reckoning. The United States has reached an appalling milestone: more than one million new coronavirus cases every week. Hospitals in some states are full to bursting.…

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Melania Trump Reveals White House Christmas Decorations

The first lady has overseen holiday decorations at the White House since 1961, when Jacqueline Kennedy hung ornaments of toys, birds and angels themed to “The Nutcracker” ballet on a Christmas tree in the Blue Room. This year was no different. In a one-minute video posted to Twitter on Monday, Melania Trump unveiled this year’s…

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Oregon Nurse Is Placed on Leave Over TikTok Video Mocking Masks

A nurse in Oregon who mocked the state’s pandemic protocols in a video that circulated on TikTok by saying she does not wear a mask in public has been placed on administrative leave, her employer said. The nurse, Ashley Grames, is an employee at Salem Health, which operates Salem Health Hospital in Salem, Ore., and…

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