The existing drug estradiol can inhibit tumor growth in a subtype of triple-negative breast cancer. The researchers may soon test the repurposed drug in a phase II clinical trial. New findings may improve patient outcomes, as an existing drug inhibits the growth of an aggressive form of breast cancer. Triple-negative breast cancer is an aggressive…
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Frogs are terrific jumpers. Ask any child who has tried to catch one. Or read Mark Twain’s story, “The Celebrated Jumping Frog of Calaveras County.” It helped make his name as a writer. Like Twain, Chris Richards, a researcher at Harvard, came to frogs early, as a first-year graduate student. Like Twain, he writes about…
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Alexa Chung is a basket case, a man eater, and an insecure shell of her former self. Just ask Google News, which hoards crazy headlines about her with the fanatic, frenetic energy of Gretchen Weiner stashing secrets. “It’s gotten to the point where I hear myself talk and know what the headline is going to…
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It Ain’t Over Till It’s Over: So far, history has proved Mr. Frank half-correct. The Dow Jones index, which had peaked around 17,000 at the height of the ’90s boom, has merely passed 26,000, not 36,000. But the dot-coms, as you might have noticed, did not exactly vanish. That old apple of Mr. Blodget’s eye,…
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Anyone who has watched a beloved brand fade into oblivion or a niche studio suddenly explode onto the scene knows fashion is as much a business as it is a form of creative expression. Behind every successful brand, dozens—even hundreds—of number-crunchers make the decisions that keep it afloat. We may take our cues from the…
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Moschino’s long-awaited collaboration with H&M is almost upon us, and we finally have our first look at the ad campaign featuring Gigi Hadid. In a series of new photos revealed by WWD, we get to see the color palette of H&M’s Moschino collection. Featuring silver, gold, and sparkly fabrics, contrasted with a lot of neutral…
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Single what? Kyle who? The full names are now on the food map. SingleThread is the restaurant and inn that the chef Kyle Connaughton and his wife, Katina Connaughton, opened without much fanfare in early December 2016 in Healdsburg, Calif. The Michelin Guides soon picked up the scent and within 10 months awarded the restaurant…
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The really special thing about visiting a big city isn’t the culture or the food, but the energy that hums throughout. It’s been built up by generations of people experiencing big moments, discovering new things, falling in love, and having their hearts broken. Taken all together, it’s an uncountable amount of heady memories that have…
DetailsEsophageal thrush is a fungal infection of the esophagus or food pipe. Doctors sometimes call it esophageal candidiasis. The food pipe is the tube that connects the mouth and throat to the stomach. Although anyone can develop esophageal thrush, it is more common in people with weakened immune systems, especially those with HIV or AIDS.…
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