Sitting All Day May Increase Your Risk of Dying From Cancer

Sitting for hours on end could heighten someone’s risk of later dying from cancer, according to a sobering new study of the relationship between inactivity and cancer mortality. The study was epidemiological, providing a snapshot of people’s lives, so it cannot prove cause and effect. But the findings suggest that extremely sedentary people can be…

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Weird Times Call for Even Weirder Shoes

While there may not be any one word to describe our collective state of limbo, one footwear category has emerged, like a gentle intervention, to help us stand astride the void. It’s a water shoe moment. Water shoes, or amphibious footwear, as those in the industry refer to it, were made for moments defined by…

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Those Who Can’t March Can Still Make a Difference

Amid the two suffocating pandemics Americans confront today — of contagious disease and systemic racism — what can cancer patients do? Like other people with compromised immune systems, many of us feel too vulnerable to participate in public demonstrations and yet we want to be part of the solution, not simply bystanders in the disaster.…

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Molecular simulations show how drugs block key receptors

Many pharmaceuticals work by targeting what are known as «G-protein-coupled receptors». In a new study, scientists from Uppsala University describe how they have been able to predict how special molecules that can be used in new immunotherapy against cancer bind to these receptors. The researchers’ calculation methods, presented in the journal Angewandte Chemie are a…

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Study confirms «classic» symptoms of COVID-19

A persistent cough and fever have been confirmed as the most prevalent symptoms associated with COVID-19, according to a major review of the scientific literature.    Other major symptoms include fatigue, losing the ability to smell and difficulty in breathing.   The study ratifies the list of symptoms listed by the World Health Organisation at the start of the pandemic.  The researchers…

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Treating leukaemia more effectively

In the current issue of Communications Biology, Professor Jindrich Cinatl from the Institute for Medical Virology at Goethe University and Professor Martin Michaelis from the School of Biosciences at the University of Kent report on their investigations with nelarabine on different cell lines. «Nelarabine is the precursor of the drug, a prodrug, that does not…

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Genomes front and center of rare disease diagnosis

Cambridge UK, 24 June 2020: A research programme pioneering the use of whole genome sequencing in the NHS has diagnosed hundreds of patients and discovered new genetic causes of disease. Whole genome sequencing is the technology used by the 100,000 Genomes Project, a service set up by the government which aims to introduce routine genetic…

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TB cases and deaths predicted to spike due to COVID-19

The global COVID-19 pandemic could significantly increase the global burden of tuberculosis (TB) due to disruptions to health services, and delays to diagnosis and treatment, according to new estimates published in the European Respiratory Journal. Before COVID-19, over 4,000 people were dying from TB every day. In countries where health services are strained, there is…

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Turning alcohol into key ingredients for new medicines

Chemists have found a way to turn alcohol into amino acids, the building blocks of life. In a study published Monday in the journal Nature Chemistry, researchers explained the transformation, which involves selectively identifying and replacing molecular bonds with unprecedented precision. The finding may make it easier to create some medications by expanding the types…

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