Hyperactive FOXA1 reprograms endocrine-resistant breast cancer to become metastatic
A team led by researchers at Baylor College of Medicine and Harvard Medical School has unveiled a novel mechanism that helps explain how endocrine-resistant breast cancer acquires metastatic behavior, opening the possibility of new therapeutic strategies. Published in the Proceedings of the National Academy of Sciences, the study shows that hyperactive FOXA1 signaling, which previously…
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