Researchers who generated a strain of SARS-CoV-2 that can infect mice used it to produce a new mouse model of infection that may help facilitate testing of COVID-19 vaccines and therapeutics. Notably, they used their mouse model to test and confirm the protective efficacy of a COVID-19 vaccine candidate. The ongoing COVID-19 pandemic has prioritized…
Billions of dollars are being invested in the development of vaccines against the coronavirus. Until one arrives, many scientists have turned to tried-and-true vaccines to see whether they may confer broad protection, and may reduce the risk of coronavirus infection, as well. Old standbys like the Bacille Calmette-Guerin tuberculosis vaccine and the polio vaccine appear…
In a world plagued by pandemic, Vietnam seemed like a miracle. As months went by without a single recorded coronavirus death, or even a confirmed case of local transmission, residents began leaving their face masks at home. Noodle shops resounded with the clack of chopsticks and sipped broth. Schools opened. And lured by good deals,…
Severe gum disease and tooth loss may be linked to an increased risk for developing dementia, a new study has found. Researchers looked at 8,275 men and women whose average age was 63 at the start of the study. Over an average follow-up of more than 18 years, 19 percent of them developed Alzheimer’s disease…
This obituary is part of a series about people who have died in the coronavirus pandemic. Read about others here. The challenges kept coming at Renada McGuire, and she kept rising to the occasion. Whether raising six children as a single mother, fighting through kidney and heart problems or learning how to fish, Ms. McGuire,…
Is it possible to reopen school buildings in the fall in a way that keeps kids, educators, staff and their families and communities safe from Covid-19? Is it possible not to do so without harming them in other ways? Already, school closures have set children behind academically. More than 20 million children rely on school…
In a new analysis, pediatric researchers have estimated that the states’ decisions to close schools last spring likely saved tens of thousands of lives from Covid-19 and prevented many more coronavirus infections. The findings come amid a worldwide debate on whether, when and how to reopen schools, including for some 56 million American students, kindergarten…
Once again, the coronavirus is ascendant. As infections mount across the country, it is dawning on Americans that the epidemic is now unstoppable, and that no corner of the nation will be left untouched. As of Tuesday, the pathogen had infected at least 4.3 million Americans, killing almost 150,000. Many experts fear the virus could…
COLUMBUS – Researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) and The Ohio State University Wexner Medical Center are conducting a new clinical trial to determine if an oral cancer drug called ibrutinib can also help patients with cancer…
A large-scale trial has found a treatment with pimavanserin substantially reduced psychotic symptoms and reduced risk of relapse of those symptoms compared to placebo in people with dementia, a condition for which no treatments are currently licensed. New data presented at the Alzheimer’s Association International Conference indicates that pimavanserin leads to a robust reduction…