Bottom Line: Younger patients with resected melanoma had some benefit from adjuvant treatment with the anti-VEGF therapeutic bevacizumab (Avastin) while older patients with resected melanoma did not. Preclinical data showed that VEGF, a protein that promotes angiogenesis and is the target of bevacizumab, decreased with age, and was superseded by the protein sFRP2 in promoting…
Recent FDA chief Dr. Scott Gottlieb argued that he’d “rather try to get everyone in masks” and “try to get them in high-quality masks because we know it’s going to slow down the transmission.” Against this backdrop, a new study published in Risk Analysis, “Reinventing cloth masks in the face of pandemics,” by Stephen Salter,…
(Boston)–The field of forensic anthropology is a relatively homogenous discipline in terms of diversity (people of color, LGBTQ+ individuals, people with mental and physical disabilities, etc.) and this is highly problematic for the field of study and for most forensic anthropologists. At the core of the forensic sciences are basic sciences and the STEM fields,…
ERA-EDTA is organizing a series of e-seminars to initiate open discussion within the nephrology community on how to apply the findings of recent trials to the needs of patients. The e-seminars will bring together kidney disease experts to provide a detailed update on the latest studies, give information on study design, study population and results,…
BOSTON – For the first time, researchers have successfully created airway basal stem cells in vitro from induced pluripotent stem cells by reprogramming blood cells taken from patients. Given that airway basal cells are defined as stem cells of the airways because they can regenerate the airway epithelium in response to injury, this study may…
Conventional plastic is made from oil. The production of plastic is not sustainable, and it can contain substances we know are dangerous if ingested. In recent years, bioplastics have come onto the market as an alternative to conventional plastic. Bioplastic has some apparent advantages: it is usually made from recycled material or plant cellulose, it…
Vaccine experts peppered officials at the Food and Drug Administration with a range of questions on Thursday about its guidelines for approving a coronavirus vaccine, pushing the agency on whether it should wait longer to collect more safety data and whether an emergency approval could jeopardize the outcome of the broader clinical trials. The stakes,…
Months into the school year, school reopenings across the United States remain a patchwork of plans: in-person, remote and hybrid; masked and not; socially distanced and not. But amid this jumble, one clear pattern is emerging. So far, schools do not seem to be stoking community transmission of the coronavirus, according to data emerging from…
The Food and Drug Administration said on Thursday that it had formally approved remdesivir as the first drug to treat Covid-19, a move that indicated the government’s confidence in its safe and effective use for hospitalized patients. The F.D.A. said the drug had been approved for adults and pediatric patients 12 years of age and…
It’s good to have friends, for humans and chimpanzees. But the nature and number of those friends change over time. In young adulthood, humans tend to have a lot of friendships. But as they age, social circles narrow, and people tend to keep a few good friends around and enjoy them more. This trend holds…