Low levels of choline in pregnant Black American women associated with higher levels of stress

AURORA, Colo. (November 16, 2020) – Researchers at the University of Colorado Anschutz Medical Campus have found that many pregnant Black Americans have low levels of choline, an essential nutrient that aids in prenatal brain development. Stress caused by institutional racism may play a role. The study, out now in Schizophrenia Bulletin, also found that…

A novel monoclonal antibody therapy cuts LDL cholesterol by half in a high-risk patient population,

The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol–the so-called “bad” cholesterol–by 50 percent in patients with severe hypercholesterolemia whose condition is resistant to standard treatments, a phase 2 study from the Icahn School of Medicine of Mount Sinai and other global academic sites has found. Results from the study sponsored by Regeneron, are being…

Omega-3 fatty acids vs corn oil, major adverse cardiovascular events in patients at high risk

What The Study Did: This randomized trial examines the effects on cardiovascular outcomes of a carboxylic acid formulation of EPA and DHA (omega-3 CA) with documented favorable effects on lipid and inflammatory markers in patients with atherogenic dyslipidemia and high cardiovascular risk. Authors: Steven E. Nissen, M.D.,of the Cleveland Clinic Heart and Vascular Institute in Cleveland,…

Outcomes for out-of-hospital cardiac arrest during COVID-19 pandemic

What The Study Did: This study used a large U.S. registry of out-of-hospital cardiac arrests to asses the association between the COVID-19 pandemic and the outcomes of out-of-hospital cardiac arrests, including in areas with low and moderate COVID-19 disease. Authors: Paul S. Chan, M.D., M.Sc., of Saint Luke’s Mid America Heart Institute in Kansas City, Missouri, is the corresponding…