Multi-population risk scores could improve risk prediction for inflammatory bowel diseases, study finds

Using genetic data from nearly 30,000 people, Mount Sinai researchers have built risk scores from a combination of datasets representing distinct ancestral populations that improve prediction of risk for inflammatory bowel diseases (IBD) including Crohn’s disease and ulcerative colitis. The study was published in Gastroenterology on December 24. The researchers found that polygenic risk scores,…

Fathers Health Tied to Pregnancy Loss

A father’s poor health before conception may increase the risk for pregnancy loss, a new study suggests. Researchers analyzed records from an employee insurance database that included data on 958,804 pregnancies between 2007 and 2016, along with information on the health of the parents for an average of about four years before conception. The study…

How Confident Can You Be in a Coronavirus Test?

‘Not detected’ doesn’t mean it’s not there Many coronavirus test results already say “detected” or “not detected” as their default readout, a distinction that several experts call more useful. “‘Not detected’ really points to the moment,” said Dr. Valerie Fitzhugh, a pathologist at Rutgers University. “It wasn’t detected today. That doesn’t mean I won’t have…