Being treated by family members as irrelevant — the attachment trauma, or being a witness to ongoing patterns of abuse — creates another kind of psychological pattern. People’s identity is formed around questions like “What did I do wrong?” or “What could I have done differently?” That becomes the central preoccupation of their lives. The…
“Yes,” Meghan said, “this was very, very clear.” Later, we learned just how clear it was. She recalled what she told her husband: “It was like, these are the thoughts that I’m having in the middle of the night that are very clear, and I’m scared, because this is very real. This isn’t some abstract…
Proponents of remote audits say they can do the same thing virtually. Peter Miller, president of Dynamic Compliance Solutions, of New Jersey, which helps life science companies comply with F.D.A. regulations, says his remote audit kit can do a great inspection. The kit features a tiny 360-degree camera, which an on-site host carries on a…
In the hustle to score an elusive vaccine appointment, the leftover dose has become the stuff of pandemic lore. Extra shots — which must be used within hours once taken out of cold storage — have been doled out to drugstore customers buying midnight snacks, people who are friends with nurses and those who show…
A year ago, infectious disease doctor Christine Johnston was leading a study on the use of hydroxychloroquine for the treatment of people with COVID-19. The trial launched at the end of March, when the disease was putting the world on pause and killing thousands. Hydroxychloroquine showed promise in studies done in test tubes rather than…
Neuroendocrine tumours are cancers that begin in specialised cells called neuroendocrine cells. These cells have traits similar to those of nerve cells and hormone-producing cells. Neuroendocrine tumours, while rare, can occur anywhere in the body. Most affect the cardiothoracic region, eg lungs, appendix, small intestine, pancreas as well as the rectum. There are many types…
COLUMBUS, Ohio – A new SARS-CoV-2 vaccine candidate, developed by giving a key protein’s gene a ride into the body while encased in a measles vaccine, has been shown to produce a strong immune response and prevent SARS-CoV-2 infection and lung disease in multiple animal studies. Scientists attribute the vaccine candidate’s effectiveness to strategic production…
While receiving just one dose of a two-dose SARS-CoV-2 vaccine tends to decrease infections in the short-term if it produces a strong immune response, it may increase the potential for the virus to “escape” therapies in the longer-term if one-dose vaccinal immunity is weak, reports a new modeling study “[O]ur work emphasizes that the impact…
TUCSON, Ariz., March 9, 2021 — Critical Path Institute’s (C-Path) Patient-Reported Outcome (PRO) Consortium announces the qualification of the Diary for Irritable Bowel Syndrome Symptoms-Constipation (DIBSS-C) by the U.S. Food and Drug Administration (FDA). The DIBSS-C was developed by the PRO Consortium’s Irritable Bowel Syndrome (IBS) Working Group to support symptom-based efficacy endpoints in clinical…
An analysis of SARS-CoV-2 genome diversity in more than 1,000 people in the United Kingdom suggests that if viral mutations do arise, they can be transmitted in some cases but they rarely persist in subsequent transmissions. “Our observations indicate the within-host emergence of vaccine- and therapeutic-escape mutations is likely to be relatively rare,” say the…