Modulating rapamycin target protein promotes autophagy, lowering toxic Huntingtin protein

Researchers world-wide are focused on clearing the toxic mutant Huntingtin protein that leads to neuronal cell death and systemic dysfunction in Huntington’s disease (HD), a devastating, incurable, progressive neurodegenerative genetic disorder. Scientists in the Buck Institute’s Ellerby lab have found that the targeting the protein called FK506-binding protein 51 or FKBP51 promotes the clearing of…

Clinics Close, but Abortion Continues

Among women in the study, nearly half reported using the licensed abortion drug misoprostol or another medication in their most recent attempt to self-terminate a pregnancy, while 38 percent used herbs they heard could induce abortion, and nearly 20 percent used a physical method, such as being hit in the abdomen. Nearly 28 percent said…

Medical AI models rely on ‘shortcuts’ that could lead to misdiagnosis of COVID-19

Artificial intelligence promises to be a powerful tool for improving the speed and accuracy of medical decision-making to improve patient outcomes. From diagnosing disease, to personalizing treatment, to predicting complications from surgery, AI could become as integral to patient care in the future as imaging and laboratory tests are today. But as University of Washington…