On the Pointlessness of Pointy Shoes

One also could not easily kneel, or pray, in such shoes, which were sometimes known as “Satan’s claws.” In 1215, Pope Innocent III prohibited clergy members from wearing, among other things, “shoes with embroidery or pointed toes.” The edict was unsuccessful enough that Pope Urban V tried again in 1362. Poulaines swept into England in…

Does cannabis affect brain development in young people with ADHD? Too soon to tell, reports Harvard Review of Psychiatry

June 18, 2021 – At least so far, the currently limited research base does not establish that cannabis has additional adverse effects on brain development or functioning in adolescents or young adults with attention-deficit/hyperactivity disorder (ADHD), concludes a review in the July/August issue of Harvard Review of Psychiatry. The journal is published in the Lippincott…

Will reduction in tau protein protect against Parkinson’s and Lewy body dementias?

IMAGE: Laura Volpicelli-Daley view more  Credit: UAB BIRMINGHAM, Ala. – Will a reduction in tau protein in brain neurons protect against Parkinson’s disease and Lewy body dementias? A new study, published in the journal eNeuro, suggests the answer is no. If this is borne out, that result differs from Alzheimer’s disease, where reducing endogenous tau levels…

Picky neurons

IMAGE: The agony of choice: despite being in contact with both eyes, neurons in the mouse visual thalamus only transfer information from one retina. view more  Credit: MPI of Neurobiology / Kuhl The visual thalamus is classically known to relay visual stimuli coming from the retina to the cerebral cortex. Researchers from the Max Planck Institute…

Overcoming a newly recognized form of resistance to modern prostate cancer drugs

IMAGE: Neuroendocrine prostate cancer cells. view more  Credit: Dr. Aaron Udager, Michigan Medicine Cancer cells have an uncanny ability to evolve and adapt to overcome the treatments used against them. While patient survival has been extended by modern drugs that block the production or action of male hormones that fuel prostate cancer — androgen receptor inhibitors…